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An essential role in germline development for a P-granule associated novel protein in the model organism Caenorhabditis elegans and RNAi in the ubiquitous parasitic nematode Ascaris suum
(University of Missouri--Columbia, 2009)
The germline RNA helicases (GLHs) are constitutive components of P granules and important for fertility in C. elegans. Discovered as a GLH-1 partner, the P-granule associated novel protein (PAN-1) is important both in ...
Dicer interacts with the P-granule component GLH-1 : both localize to C. elegans nuclear pores and to stress-induced oocyte RNP granules
(University of Missouri--Columbia, 2010)
of GLH-1, are regulated by proteosomal degradation and are much increased when the Jun N-terminal kinase KGB-1 is missing in the kgb-1(um3) null. In the adult C. elegans germline DCR-1 is located throughout the cytoplasm as well as at the inner nuclear...